Before adding exfoliation during GLP-1 treatment, review what is already on your bathroom shelf.

Check active products and skin type

AAD warns that exfoliation alongside prescription retinoids, retinol or benzoyl peroxide may worsen dryness or cause breakouts. Mechanical methods may irritate dry, sensitive or acne-prone skin. It advises avoiding strong chemical or mechanical exfoliation with darker skin tones or a history of dark marks after skin injuries. Never exfoliate open wounds or sunburned skin. [1]

Read an AHA label beyond the percentage

FDA explains that an alpha hydroxy acid (AHA) product's exfoliating effect depends on acid type, concentration, pH and other ingredients. Glycolic and lactic acids are common AHAs. Follow directions and warning statements. [2]

FDA recommends an AHA label warning about increased sun sensitivity and sunburn: use sunscreen and protective clothing, and limit sun exposure during use and for a week afterward. This is not a universal warning for every exfoliating ingredient. [2]

Decide whether to add it

AAD recommends a dermatologist's assessment if you are unsure about exfoliating. [1]

These US sources do not establish a GLP-1-specific exfoliation benefit. For an unfamiliar product, read our product-testing guide.

This article provides general education, not a diagnosis or an individual treatment plan. Medication information refers to US sources. Discuss medication, nutrition and cosmetic treatment decisions with qualified clinicians.

Sources

  1. How to safely exfoliate at home, updated February 6, 2026American Academy of Dermatology, US patient guidance↩ Back to text
  2. Alpha Hydroxy AcidsUS Food and Drug Administration↩ Back to text